Research Elective

Elective Director: Dr Samaresh Dasgupta

You are responsible for reading the referenced textbook (available via Rowan online library).  There will be a short quiz at the end of your rotation that you must score > 70%.

I would like you to create and share a basic schedule template for yourself for the remainder of the month.

You will be asked for periodic updates on your progress over the course of your rotation.

In addition to the stated goals and objectives stated below, this is the time to devote a great deal of effort to your required research project.

Required reading: Hulley, Stephen B., et al. Designing clinical research. Lippincott Williams & Wilkins, 2013.

  • dasguptas@ihn.org

Goals

  • Learn techniques of analyzing biomedical research.
  • Understand methods of hypothesis and development and testing.
  • Understand various types of study design and methodology.
  • Learn various methods of obtaining consent for biomedical research.
  • Understand basic statistical methods.
  • Understand the ramifications of ethical considerations in research.
  • Learn the skills to develop a manuscript that is acceptable for publication in a peerreview journal.
  • Understand grants and funding issues of research.

Objectives

  • Demonstrate an understanding of the advantages and disadvantages of various study designs including the randomized clinical trial and case control cohort and cross sectional studies.
  • Demonstrate an understanding of null and alternative hypotheses.
  • Demonstrate an understanding of the practical and ethical ramifications of implied and non­implied consent as they apply to hospital and pre­hospital research.
  • Understand the differences between independent and dependent variables.
  • Demonstrate an understanding of methodologies and variable types analyzed by the following statistical tests.
  • Demonstrate an understanding of alpha, beta and statistical power.
  • Demonstrate an understanding of the differences between statistical and clinical significance.
  • Define sensitivity, specificity, positive predictive value, and negative predictive value.
  • Define mean, median, mode, standard deviation and variance.
  • Demonstrate an understanding of confidence intervals.
  • Describe correlation and regression to the mean.
  • Discuss the advantages of single and double blind studies.
  • Demonstrate facility with at least one computer statistical program.
  • Demonstrate an understanding of basic ethical issues in research including consent and researchers’ interactions with corporate funding sources.
  • Demonstrate an understanding of research funding.
  • Demonstrate the skills necessary to write a publishable manuscript.